The Ten Books on Architecture, 8.3.11

Vitruvius  translated by Morris Hicky Morgan

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11There are also springs which issue exceedingly bitter, owing to a bitter juice in the soil, such as the river Hypanis in Pontus. For about forty miles from its source its taste is very sweet; then it reaches a point about one hundred and sixty miles from its mouth, where it is joined by a very small brook. This runs into it, and at once makes that vast river bitter, for the reason that the water of the brook becomes bitter by flowing through the kind of soil and the veins in which there are sandarach mines.

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